Yes, you can use your LQ-4wire units to replace the now discontinued Voice2 units.
Using a pair of LQ 4wire units (locally & remote) you can connect the following panels over IP back to a central matrix like a Pico frame.
V-series panels
I-stations
ICS1008/1016E panels

In the LQ CCM (web browser) set up DIRECT channels and place a 4wire port from the local and remote LQ units in to a Direct channel
Then set the LQ connected to the matrix (MVX port) to its have 4wire port function set to > "connect to matrix"
Then set the LQ connected to directly to the intercom panel (matrix comms) to have its have 4wire port function set to > "connect to panel"